5-FU + Cisplatin + RT + Surgery

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Indication

Neoadjuvant chemoradiation +/- surgery for resectable cancer

  • 5-FU 15 mg/kg/d iv bolus d1-5 week 1 and 6
  • Cisplatin 70 mg/m2 iv d7 week 1 and 6
  • Concurrent radiotherapy 40 Gy
  • Surgery

References

Walsh TN et al. A comparison of multimodal therapy and surgery for esophageal adenocarcinoma. N Eng J Med 1996; 335:462