Salvage chemotherapy of MOPP-resistant Hodgkin's disease
- Doxorubicin (Adriamycin)
- DTIC (dacarbazine)
- CCNU (lomustine)
Continuous infusion variant
- Doxorubicin 25 mg/m2 by continuous infusion daily for 2 days
- Dacarbazine 200 mg/m2 by continuous infusion daily for 5 days
- Bleomycin 5 U/m2 intravenously on days 1 and 5
- CCNU 40 mg/m2 on day 1
- Prednisone 40 mg/m2 daily on days 1-5
Treatment was repeated every 28 days.
Tannir N et al Long-term follow-up with ABDIC salvage chemotherapy of MOPP-resistant Hodgkin's disease. J Clin Oncol 1983 Jul;1(7):432-9.
Smith MR et al Continuous infusion ABDIC therapy for relapsed or refractory Hodgkin's disease. Cancer 1994 Feb 15;73(4):1264-9.