BeGeV

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Hodgkin disease

salvage regimen in relapsed Hodgkin's lymphoma

Regimen

phase II study

  • Gemcitabine 800 mg/m2 on days 1 and 4
  • Vinorelbine 20 mg/m2 on day 1,
  • Bendamustine 90 mg/m2 on days 2 and 3
  • Prednisolone 100 mg per day was administered on days 1 to 4

Patients received four cycles of the BeGEV regimen administered every 21 days. Growth factor support with granulocyte colony-stimulating factor (G-CSF) was administered at each cycle. Patients received Pneumocystis pneumonia prophylaxis and antiemetics in accordance with institutional guidelines.

References

BBendamustine in Combination With Gemcitabine and Vinorelbine Is an Effective Regimen As Induction Chemotherapy Before Autologous Stem-Cell Transplantation for Relapsed or Refractory Hodgkin Lymphoma: Final Results of a Multicenter Phase II Study Santoro et al . J Clin Oncol 2016