CIM

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Indication

Adjuvant chemotherapy for carcinosarcoma

  • Cisplatin 20 mg/m2/d iv d1-4
  • Ifosfamide 1.5 g/m2/d iv d1-4
  • Mesna 120 mg/m2 iv loading dose followed by 1.5 g/m2/d iv d1-4
  • Q3w x 3 cycles

References

Wolfson AH et al. A gynecologic oncology group randomized trial of whole abdominal irradiation (WAI) vs cisplatin-ifosfamide-mesna (CIM) in optimally debulked stage I-IV carcinosarcoma (CS) of the uterus. 2006 ASCO annual meeting. Abstract 5001