CLAG

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Indication

Relapsed or refractory acute myeloid leukemia

Regimen

  • Cladribine 5 mg/m2/d iv over 2 hrs d1-5
  • Cytarabine (Ara-C) 2 g/m2/d iv over 4 hrs d1-5
  • Filgrastim (Neupogen) 300 mcg sc d0-5

References

Robak T et al. Combination regimen of cladribine (2-chlorodeoxyadenosine), cytarabine and G-CSF (CLAG) as induction therapy for patients with relapsed or refractory acute myeloid leukemia. Leuk Lymphoma 2000; 39:121