ECF + surgery + ECF

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Indication

Perioperative chemotherapy for resectable adenocarcinoma of esophagogastric junction and lower esophagus

  • Epirubicin 50 mg/m2 iv d1
  • Cisplatin 60 mg/m2 iv d1
  • 5-FU 200 mg/m2/d civi
  • Q3w x 3 cycles
  • Surgery 3-6 weeks after chemotherapy

6-12 weeks after surgery, repeat the chemotherapy:

  • Epirubicin 50 mg/m2 iv d1
  • Cisplatin 60 mg/m2 iv d1
  • 5-FU 200 mg/m2/d civi
  • Q3w x 3 cycles

References

Cunningham D et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Eng J Med 2006; 355:11