EPOCH

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Regimen

Etoposide 50 mg/m2/day continuous infusion 	days 1-4
Doxorubicin 10 mg/m2/day continuous infusion	days 1-4
Vinristine 0.4 mg/m2/day continuous infusion	days 1-4
Cyclophosphamide 750 mg/m2 IV			day 5
Prednisolone 60 mg/m2/day PO			days 1-5
G-CSF 5ug/kg/day SC 				days 6-ANC >5 x 109/L
Etoposide, doxorubicin and vincristine can be admixed in the same solution
Vincristine is NOT capped
Repeat cycle every 21 days 

References

Gutierrez M et al. Role of a doxorubicin-containing regimen in relapsed and resistant lymphomas: An 8-year follow-up study of EPOCH. J Clin Oncol 2000; 18:3633