From OncoWiki


Indolent NHL

Fludarabine 20 mg/m2 IV on days 1-5
Cyclophosphamide 1000 mg/m2 IV on day 1

Bactrim DS 1 tablet PO bd

Repeat cycle every 21-28 days


Hochster H et al. Efficacy of cyclophosphamide (CYC) and fludarabine (FAMP) as first-line therapy of low-grade non-Hodgkin's lymphoma (NHL) Blood 1994: 84 (Suppl 1): 383a

Chronic Lymphocytic Leukemia

Fludarabine 30 mg/m2/d iv d1-3
Cyclophosphamide (Cytoxan) 250 mg/m2/d iv d1-3
Q4w x 6 cycles


Eichhorst BF et al. Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia. Blood 2006; 107:885