Flu Bu ATG - Slavin

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  • Fludarabine (Fludara) 30 mg/m2 IV once per day on days -10 to -5 (6 consecutive days)
  • Busulfan (Myleran) 4 mg/kg/day PO on days -6 to -5 (2 consecutive days) or IV Busulfex 3.2 mg/kg days -6 to -5
  • ATG-Fresenius 10 mg/kg/day on days -4 to -1 (4 consecutive days)

References

  1. Slavin S, Nagler A, Naparstek E, Kapelushnik Y, Aker M, Cividalli G, Varadi G, Kirschbaum M, Ackerstein A, Samuel S, Amar A, Brautbar C, Ben-Tal O, Eldor A, Or R. Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases. Blood. 1998 Feb 1;91(3):756-63. link to original article contains verified protocol PubMed