IFL + Bevacizumab

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Indication

Chemotherapy for stage IV (metastatic) cancer

  • Leucovorin 20 mg/m2 iv bolus qw x 4 wks every 6 wks
  • 5-FU 500 mg/m2 iv bolus qw x 4 wks every 6 wks
  • Irinotecan (Camptosar, CPT-11) 125 mg/m2 iv qw x 4 wks every 6 wks
  • Bevacizumab (Avastin) 5 mg/kg iv q2w

References

Hurwitz, H et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335