XELIRI + Bevacizumab

Chemotherapy for stage IV (metastatic) cancer

• Capecitabine (Xeloda) 1000 mg/m2 (750 mg/m2 for pts > 65) po bid x 14 days q3w
• Irinotecan (Camptosar, CPT-11) 250 mg/m2 (200 mg/m2 for pts > 65) iv d1 q3w
• Bevacizumab (Avastin) 7.5 mg/kg iv d1 q3w

Patt, YZ et al. Capicitabine plus irinotecan as first-line treatment for metastatic colorectal cancer: Final safety findings from a phase II trial (abstract). 2004 ASCO annual meeting. Abstract 3602