CVD + IL-2 + IFN

Indication

Metastatic cancer

• Cisplatin 20 mg/m2/d iv d1-4 and 22-25
• Vinblastine 1.5 mg/m2/d iv d1-4 and 22-25
• Dacarbazine (DTIC) 800 mg/m2 iv d1, 22
• IL-2 9 MU/m2/d civi d5-8, 17-20, 26-29
• Interferon α-2b 5 MU/m2/d sc d5-9, 17-21, 26-30
• Q6w

References

Eton, O et al. Sequential biochemotherapy versus chemotherapy for metastatic melanoma: results from a phase III randomized trial. J Clin Oncol 2002; 20:2045