Cisplatin + 5-FU

Indication

Chemotherapy for locally advanced unresectable and metastatic cancer

• Cisplatin 100 mg/m2 iv d1
• 5-FU 1000 mg/m2/d civi d1-5
• Q4w

References

Ajani JA et al. Clinical benefit with docetaxel plus fluorouracil and cisplatin compared with cisplatin and fluorouracil in a phase III trial of advanced gastric or gastroesophageal cancer adenocarcinoma: The V-325 Study Group. J Clin Oncol 2007; 25:3205

Ajani JA et al. Quality of life with docetaxel plus cisplatin and fluorouracil compared with cisplatin and fluorouracil from a phase III trial for advanced gastric or gastroesophageal adenocarcinoma: The V-325 Study Group. J Clin Oncol 2007; 25:3210

Custem EV et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 study group. J Clin Oncol 2006; 24:4991