Cisplatin + 5-FU + RT

Indication

Concurrent chemoradiation

• Cisplatin 70 mg/m2 iv d1 q3w x 2 cycles
• 5-FU 1000 mg/m2/d civi d1-4 q3w x 2 cycles
• Concurrent radiotherapy 49.3 Gy

Followed by

• Cisplatin 70 mg/m2 iv d1 q3w x 2 more cycles
• 5-FU 1000 mg/m2/d civi d1-4 q3w x 2 more cycles

References

[Peters, WA III et al. Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix. J Clin Oncol 2000; 18:1606