Cisplatin + Docetaxel

Indication

Gastric Cancer

Chemotherapy for locally advanced unresectable and metastatic cancer

• Cisplatin 75 mg/m2 iv d1
• Docetaxel (Taxotere) 75-85 mg/m2 iv d1
• Q3w

References

Roth AD et al. Docetaxel, cisplatin; and fluorouracil; docetaxel and cisplatin; and epirubicin, cisplatin, and fluorouracil as systemic treatment for advanced gastric carcinoma: a randomized phase II trial of the Swiss Group for Clinical Cancer Research. J Clin Oncol 2007; 25:3217

Ajani JA et al. Phase II multi-institutional randomized trial of decetaxel plus cisplatin with or without fluorouracil in patients with untreated, advanced gastric, or gastroesophageal adenocarcinoma. J Clin Oncol 2005; 23:5660

Ridwelski, K et al. Combination chemotherapy with docetaxel and cisplatin for locally advanced and metastatic gastric cancer. Ann Oncol 2001; 12:47

Lung Cancer Non Small Cell

Chemotherapy for stage IV (metastatic) cancer

• Cisplatin 75 mg/m2 iv day 1
• Docetaxel (Taxotere) 75 mg/m2 iv day 1
• Q3w

References

Schiller JH et al. Comparison of four chemotherapy regimens for advanced non-small cell lung cancer. N Eng J Med 2002; 346:92