Escalated BEACOPP

Regimen

 Bleomycin 10 mg/m2 IV on Day 8
 Etoposide 200 mg/m2 IV on Day 1, 2 and 3
 Doxorubicin 35 mg/m2 IV on Day 1
 Cyclophosphamide 1250 mg/m2 IV on Day 1
 Vincristine 1.4 m/m2 (max 2mg) IV on Day 8
 Procarbazine 100 mg/m2 Oral Day 1 to Day 7
 Prednisolone 40 mg/m2 Oral Day 1 to Day 14

 GCSF from Day 8 until WBC normal
 Repeat cycle every 22 days

References

Volker Diehl et al, Standard and Increased-Dose BEACOPP Chemotherapy Compared with COPP-ABVD for Advanced Hodgkin's Disease, NEJM, Volume 348:2386-2395, June 2003