IFL + Bevacizumab

Indication

Chemotherapy for stage IV (metastatic) cancer

• Leucovorin 20 mg/m2 iv bolus qw x 4 wks every 6 wks
• 5-FU 500 mg/m2 iv bolus qw x 4 wks every 6 wks
• Irinotecan (Camptosar, CPT-11) 125 mg/m2 iv qw x 4 wks every 6 wks
• Bevacizumab (Avastin) 5 mg/kg iv q2w

References

Hurwitz, H et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335