Etoposide

Regimen

Kaposi's Sarcoma

• Etoposide (VP-16) 50 mg po qd d1-7
• Q2w

References

Evans, SR et al. Phase II evaluation of low-dose oral etoposide for the treatment of relapsed or progressive AIDS-related Kaposi's sarcoma: An AIDS Clinical Trials Group Clinical Study. J Clin Oncol 2002; 20:3236

Indication

Ovarian Epithelial Cancer

Chemotherapy for recurrent or metastatic cancer

• Etoposide (VP-16) 50-60 mg/m2 po qd x 3wks every 4 wks

References

Rose, PG et al. Prolonged oral etoposide as second-line therapy for platinum-resistant and platinum-sensitive ovarian carcinoma: a Gynecologic Oncology Group study. J Clin Oncol 1998; 16:405

Lung Cancer Small Cell

Extensive stage

• Etoposide (VP-16) 50 mg/m2 po qd x 3 weeks q4w

References

Johnson DH et al. Prolonged administration of oral etoposide in patients with relapsed or refractory small-cell lung cancer: a phase II trial. J Clin Oncol 1990;8:1613