Vinorelbine

Drug information

Navelbine

• Drug info (BC Cancer)
• Monograph (Cancercare Ca, PDF)

Indication

Cervical Cancer

Chemotherapy for stage IVB (metastatic) cancer

• Vinorelbine (Navelbine) 30 mg/m2 iv
• Qw

References

Morris, M et al. Phase II study of vinorelbine in advanced and recurrent squamous cell carcinoma of the cervix. J Clin Oncol 1998; 16:1094

Esophageal Cancer

Chemotherapy for stage IV (metastatic) cancer

• Vinorelbine (Navelbine) 25 mg/m2 iv
• Qw

References

Conroy, T et al. Phase II trial of vinorelbine in metastatic squamous cell esophageal carcinoma. European Organization for Research and Treatment of Cancer Gastrointestinal Treat Cancer Cooperative Group. J Clin Oncol 1996; 14:164

Ovarian Epithelial Cancer

Chemotherapy for recurrent or metastatic cancer

• Vinorelbine (Navelbine) 30 mg/m2 iv bolus d1 and 8
• Q3w

References

Sorensen, P et al. Phase II study of vinorelbine in the treatment of platinum-resistant ovarian carcinoma. Gynecol Oncol 2001; 81:58

Lung Cancer Non Small Cell

Chemotherapy for stage IV (metastatic) cancer

• Vinorelbine (Navelbine) 25 mg/m2 iv qw

References

Furuse K et al. Randomized study of vinorelbine (VRB) versus vindesine (VDS) in previously untreated stage IIIB or IV non-small cell lung cancer (NSCLC). The Japan Vinorelbine Lung Cancer Cooperative Study Group. Ann Oncol 1996; 7: 815

Regimen

Breast Cancer

• Vinorelbine 30 mg/m2 iv qw

References

G et al. Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study. J Clin Oncol 1994; 12:2094

Kaposi's Sarcoma

• Vinorelbine (Navelbine) 30 mg/m2 iv
• Q2w

References

Nasti, G et al. Vinorelbine is an effective and safe drug for AIDS-related Kaposi's sarcoma: results of a phase II study. J Clin Oncol 2000; 18:1550